Various embodiments disclosed herein provide for facilitating uplink interference avoidance. According an embodiment, a system can comprise receiving a request to adjust an uplink power limit of a first communication device that is generating an uplink interference above a threshold and a power adjustment value employable to adjust the uplink power limit of the first communication device. The system can further facilitate identifying a packet flow in an uplink communication with the first communication device, wherein use of the packet flow results in generating of the uplink interference above the threshold. The system can further facilitate determining whether the uplink power limit of the first communication device is able to be adjusted based on a quality of service allocated to the packet flow. The system can further facilitate transmitting a message to update the uplink power limit of the first communication device using the power adjustment value.