Methods of propagating a Cannabis cutting are provided. A method of propagating a Cannabis cutting can include: providing a coherent growth substrate comprising man-made vitreous fibres bonded with a cured binder composition, the growth substrate having a density in the range of 60 kilograms per cubic meter (kg/m3) to 70 kg/m3; inserting the Cannabis cutting into the growth substrate at a location where the growth substrate does not have a seed hole; and providing a nutrient solution having an electrical conductivity value between 1.6 milli-Siemens per centimeter (mS/cm) and 2.4 mS/cm to the Cannabis cutting in the growth substrate.