Invention Grant
- Patent Title: High-intensity focused ultrasound for heating a target zone larger than the electronic focusing zone
-
Application No.: US14390181Application Date: 2013-04-09
-
Publication No.: US11116405B2Publication Date: 2021-09-14
- Inventor: Ari Ilkka Mikael Partanen , Matthew Robert Dreher , Pavel Sergeyevich Yarmolenko , Bradford Johns Wood , Elma Natalia Carvajal Gallardo
- Applicant: Profound Medical Inc. , THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH & HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH, OFFICE OF TECHNOLOGY TRANSFER
- Applicant Address: CA Mississauga; US MD Bethesda
- Assignee: Profound Medical Inc.,THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH & HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH, OFFICE OF TECHNOLOGY TRANSFER
- Current Assignee: Profound Medical Inc.,THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF HEALTH & HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH, OFFICE OF TECHNOLOGY TRANSFER
- Current Assignee Address: CA Mississauga; US MD Bethesda
- Agency: Intrinsic Law Corp.
- International Application: PCT/IB2013/052806 WO 20130409
- International Announcement: WO2013/153506 WO 20131017
- Main IPC: A61B5/00
- IPC: A61B5/00 ; A61N7/02 ; A61B34/10 ; A61B5/01 ; A61B5/055 ; A61N7/00 ; A61B18/00 ; A61B17/00 ; A61B90/00

Abstract:
The invention provides for a medical instrument (200) comprising a magnetic resonance imaging system (202) and a high-intensity focused ultrasound system (204) with an electronically controllable and a mechanically controllable focus. Execution of instructions by a processor (244) controlling the instrument cause the processor to: receive (100) a target zone (240, 264) descriptive of a zone within the subject; divide (102) the target zone into multiple sub-zones (416, 418, 420, 422, 424, 426, 428, 430, 432, 434); determine (104) a sequence (272) for moving the transducer position to each of the multiple sub-zones; determine (106) a selected sub-zone selected from the multiple sub-zones using the sequence; repeatedly control (108) the mechanical positioning system to move the transducer to the transducer position of the selected sub-zone; repeatedly acquire (110) the magnetic resonance thermometry data; repeatedly determine (112) a temperature property map (274); repeatedly heat (114) the regions independently to the target temperature by controlling the electronically controlled focus with a temperature feedback algorithm (286); and repeatedly change (116) the selected sub-zone using the sequence.
Public/Granted literature
- US20150080705A1 HIGH-INTENSITY FOCUSED ULTRASOUND FOR HEATING A TARGET ZONE LARGER THAN THE ELECTRONIC FOCUSING ZONE Public/Granted day:2015-03-19
Information query