A system for digital self-interference cancellation includes a filter that generates a reduced-noise digital residue signal; a channel estimator that generates a current self-interference channel estimate from a digital transmit signal, the reduced-noise digital residue signal, and past self-interference channel estimates; a controller that dynamically sets the digital transform configuration in response to changes in a controller-sampled digital residue signal; a predictor that modifies output of the channel estimator to compensate for a first time delay incurred in tuning the system for digital self-interference cancellation; and a channel memory that stores the past self-interference channel estimates.