The present disclosure discloses an information interaction method, an information interaction system, and an application thereof, and belongs to the field of electronic whiteboards. In view of the problems in the prior art that an electronic whiteboard in a conference system has a large amount of data to be transmitted, requires a large interaction bandwidth, and has high network requirements, the present disclosure provides an information interaction method: When an image is annotated on the local device, the host serializes the annotation on the local device. The remote device combines the serialized data and corresponding coordinates and pressure sensing values, to calculate and draw an image for display from the data by using a GPU. The interaction method is applied to the electronic whiteboard in the conference system, thereby realizing multi-party real-time interactive whiteboard collaboration, which is supported in both local conferences and teleconferences.