Invention Grant
- Patent Title: Dementia therapeutic agent combining pyrazoloquinoline derivative and memantine
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Application No.: US16607459Application Date: 2018-05-30
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Publication No.: US11147803B2Publication Date: 2021-10-19
- Inventor: Mai Miyamoto , Sadaharu Kotani
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- International Application: PCT/JP2018/020649 WO 20180530
- International Announcement: WO2018/221550 WO 20181206
- Main IPC: A61K31/4745
- IPC: A61K31/4745 ; A61K31/4375 ; A61P25/28 ; A61K31/13

Abstract:
There is provided a therapeutic agent for Alzheimer's disease for combined use of (S)-7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1H-pyrazolo[4,3-c]quinoline-4(5H)-one represented by formula (I): or a pharmaceutically acceptable salt thereof, and memantine represented by formula (II): or a pharmaceutically acceptable salt thereof.
Information query
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