A process analytic system includes an analytic sensor configured to sense a characteristic of a fluid. The process analytic system also includes measurement circuitry coupled to the analytic sensor and configured to generate an indication of the characteristic of the fluid. The process analytic system includes a processor coupled to the measurement circuitry and configured to receive the indication of the characteristic of the fluid and calculate a sensor-related output based on the indication of the characteristic of the fluid. In addition, the process analytic system includes a diagnostics component configured to determine a rate of degradation of the analytic sensor based on the sensor-related output and a reference value, wherein the rate of degradation is compared to a pre-selected threshold.