A catheter protection device and method for securing a catheter to a patient's body to prevent the unauthorized and possibly traumatic removal of a catheter. The device is thin, breathable and not easily removed by an agitated or mentally incompetent patient. The device is constructed of a base, adhesives, and a sleeve. The edges of the base each contain a section of adhesive wherein mid-portion of the base remains uncovered by adhesive. The open sleeve is permanently attached to an edge of the base. Once a catheter has been placed in an open sleeve, the sleeve will be folded such that the rear portion of the sleeve attached to the nearest edge of the base creating a closed sleeve surrounding the catheter. The catheter protection device may be placed against a patient's body with the adhesive edges of the base and an adhesive covered catheter sleeve adjacent to a patient.