A medical system including a support structure including a proximal link and a distal link, and a base joint coupling the proximal link of the support structure to a base, wherein the proximal link is configured to rotate about a first axis associated with the base joint. The system also includes a linkage mechanism coupling the proximal link to the distal link. The system also includes an instrument support coupled to the distal link, wherein the instrument support has an orientation relative to the base in a first configuration of the support structure, and wherein the linkage mechanism maintains the orientation of the instrument support relative to the base as the support structure is moved into a second configuration in which the support structure is rotated relative to the base about the first axis and the distal link is extended from the proximal link.