The technology disclosed relates to buffer-based inter-node streaming of configuration data over a network fabric. In particular, the technology disclosed relates to a runtime processor configured to load and execute a first subset of configuration files in a set of configuration files on a first reconfigurable processor operatively coupled to a first processing node, load and execute a second subset of configuration files in the set of configuration files on a second reconfigurable processor operatively coupled to a second processing node, and use a first plurality of buffers operatively coupled to the first processing node, and a second plurality of buffers operatively coupled to the second processing node to stream data between the first reconfigurable processor and the second reconfigurable processor to load and execute the first subset of configuration files and the second subset of configuration files.