- 专利标题： Methods and system for ultrasonic targeted drug delivery in cystic fluids, such as the cerebrospinal fluid, using buoyancy specific drug carriers
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申请号： US16360153申请日： 2019-03-21
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公开(公告)号： US11191937B2公开(公告)日： 2021-12-07
- 发明人: Jae H. Choi , Keith Baker , Alexander Klose , John Pile-Spellman
- 申请人： Advanced CSF Therapies, LLC
- 申请人地址： US NY Mineola
- 专利权人： Advanced CSF Therapies, LLC
- 当前专利权人： Advanced CSF Therapies, LLC
- 当前专利权人地址： US NY Mineola
- 代理机构： Lombard Geliebter LLP
- 代理商 Antonio Papageorgiou
- 主分类号： A61M31/00
- IPC分类号： A61M31/00 ; A61M37/00 ; A61B17/34 ; A61M27/00
摘要：
A method for delivering drugs into cystic fluid, the method comprising injecting a drug delivery system (DDS) into a cystic fluid space at an injection site, the DDS comprising at least one therapeutic agent encapsulated in biodegradable polymers, applying ultrasonic energy proximal to the injection site, and controlling the at least one of buoyancy, delivery location, mixing, and dispersion of the DDS to a targeted area using the ultrasonic energy.
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