There is provided a cartridge for an aerosol-generating system, the cartridge including: a first compartment having a first air inlet and a first air outlet, the first compartment containing a nicotine source including a first carrier material impregnated with between about 1 milligram and about 40 milligrams of nicotine; and a second compartment having a second air inlet and a second air outlet, the second compartment containing a lactic acid source including a second carrier material impregnated with between about 2 milligrams and about 60 milligrams of lactic acid. An aerosol-generating system is also provided, including the cartridge and an aerosol-generating device including a housing defining a cavity configured to receive at least a portion of the cartridge; and a heater configured to heat the first compartment and the second compartment of the cartridge.