A technique for fabricating a hollow core optical fiber with a controllable core region (in terms of diameter) is based upon regulating conditions (gas flow, volume, and/or temperature) within the hollow core region during the fiber draw process. The introduction of a gas, or any change in volume or temperature of the hollow core region, allows for the diameter of the hollow core region to self-regulate as a multistructured core rod (MCR) is drawn down into the final hollow core optical fiber structure. This self-regulation provides a core region having a diameter that selected and then stabilized for the duration of the draw process. The inventive process is also useful in controlling the diameter of any selected hollow region of an MCR including, but not limited to, shunts and corner capillaries disposed around the core region.