A memory sub-system configured to dynamically determine input/output sizes of write commands based on a media physical layout of a memory sub-system. The memory sub-system can identify, dynamically in response to write commands being selected for execution in media units of the memory sub-system, a portion of a media layout that maps from logical addresses identified by the write commands in the logical address space to physical addresses of memory units in the media units. Based on the media layout, an input/output size for a next write command is identified and transmitted to the host system in a response. The host system generates the next write command and configures the amount of data to be written through the next write command based on the input/output size identified in the response.