- 专利标题： Method of treating psoriasis with anti-IL23 specific antibody
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申请号： US15813767申请日： 2017-11-15
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公开(公告)号： US11208474B2公开(公告)日： 2021-12-28
- 发明人: Dennis Fitzgerald , Newman Yeilding , Jay Siegel
- 申请人： Janssen Biotech, Inc.
- 申请人地址： US PA Horsham
- 专利权人： Janssen Biotech, Inc.
- 当前专利权人： Janssen Biotech, Inc.
- 当前专利权人地址： US PA Horsham
- 代理机构： Riverside Law LLP
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/24 ; A61K9/00 ; G01N33/00 ; A61P17/06 ; A61K31/519 ; A61K45/06 ; C07K16/28 ; A61K47/22 ; A61K47/26 ; A61K39/00
摘要：
A method of treating psoriasis in a patient previously treated with and determined to be an inadequate responder to an IL-12/23p40 antibody by administering an IL-23 specific antibody, e.g., guselkumab, in a safe and effective amount and the patient achieves PASI75, PASI90, PASI100 or IGA 0 or 1 score as measured 16, 24, 32, 40 and 48 weeks after initial treatment.
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