- 专利标题： Determining position and transcriptomes of biological cells
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申请号： US16193483申请日： 2018-11-16
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公开(公告)号： US11208648B2公开(公告)日： 2021-12-28
- 发明人: Robert Vogel , Navneet Dogra , Lena Voith von Voithenberg , Aditya Kashyap , Govind V. Kaigala , Gustavo Alejandro Stolovitzky
- 申请人： International Business Machines Corporation
- 申请人地址： US NY Armonk
- 专利权人： International Business Machines Corporation
- 当前专利权人： International Business Machines Corporation
- 当前专利权人地址： US NY Armonk
- 代理机构： Amin, Turocy & Watson, LLP
- 主分类号： C12N15/10
- IPC分类号： C12N15/10 ; C12Q1/24 ; C12Q1/6806
摘要：
Techniques regarding measuring a position and transcriptome of one or more cells from a biological sample are provided. For example, one or more embodiments described herein can comprise a method, which can comprise covalently bonding a probe to a molecular structure located on a cell to label the cell according to a position of the cell with regards to a biological sample comprising the cell. The probe comprises an oligonucleotide sequence that can be indicative of the position.
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