An information processing system includes first circuitry and second circuitry. The first circuitry generates a processing command based on a recognition result of audio information acquired from a voice input device, and instructs the second circuitry to process process data based on the processing command. The second circuitry generates an execution command in response to the instruction from the first circuitry, and transmits the execution command to the information processing apparatus to instruct the information processing apparatus to execute processing of the process data.