- 专利标题: Dextrorphan prodrugs and processes for making and using them
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申请号: US16604755申请日: 2018-04-12
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公开(公告)号: US11214544B2公开(公告)日: 2022-01-04
- 发明人: Travis Mickle , Sven Guenther , Sanjib Bera
- 申请人: KEMPHARM, INC.
- 申请人地址: US IA Coralville
- 专利权人: KEMPHARM, INC.
- 当前专利权人: KEMPHARM, INC.
- 当前专利权人地址: US IA Coralville
- 代理机构: McAndrews Held & Malloy, Ltd.
- 国际申请: PCT/US2018/027266 WO 20180412
- 国际公布: WO2018/191477 WO 20181018
- 主分类号: C07D221/28
- IPC分类号: C07D221/28 ; A61K31/439 ; A61K47/54
摘要:
The presently described technology provides compositions of one or more of oxoacids, polyethylene glycols, and/or vitamin compounds chemically conjugated to dextrorphan, (+)-17-methylmorphinan-3-ol), to form novel prodrugs and compositions of dextrorphan.
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