Invention Grant
- Patent Title: Profiling microvesicle nucleic acids and uses thereof as signatures in diagnosis of renal transplant rejection
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Application No.: US16098500Application Date: 2017-05-05
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Publication No.: US11214833B2Publication Date: 2022-01-04
- Inventor: Johan Karl Olov Skog , Jamil Azzi
- Applicant: Exosome Diagnostics, Inc. , The Brigham and Women's Hospital, Inc.
- Applicant Address: US MA Waltham; US MA Boston
- Assignee: Exosome Diagnostics, Inc.,The Brigham and Women's Hospital, Inc.
- Current Assignee: Exosome Diagnostics, Inc.,The Brigham and Women's Hospital, Inc.
- Current Assignee Address: US MA Waltham; US MA Boston
- Agency: Cooley LLP
- Agent Ivor R. Elrifi; Matthew Pavao
- International Application: PCT/US2017/031212 WO 20170505
- International Announcement: WO2017/192945 WO 20171109
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C12Q1/6876 ; C12Q1/686
Abstract:
The invention relates generally to the use of microvesicle RNA signatures for diagnosis, predicting, and/or to monitor treatment efficacy, including patients who are candidates for renal transplant and/or who have received a renal transplant.
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