- 专利标题： Process for the preparation of rucaparib and novel synthesis intermediates
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申请号： US16770811申请日： 2017-12-15
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公开(公告)号： US11220507B2公开(公告)日： 2022-01-11
- 发明人: Brent Christopher Beck , Joe B. Perales , Jason D. Speake , Ilaria Ferrando
- 申请人： Advitech Advisory and Technologies SA
- 申请人地址： CH Lausanne
- 专利权人： Advitech Advisory and Technologies SA
- 当前专利权人： Advitech Advisory and Technologies SA
- 当前专利权人地址： CH Lausanne
- 代理商 Silvia Salvadori
- 国际申请： PCT/EP2017/083174 WO 20171215
- 国际公布： WO2019/115000 WO 20190620
- 主分类号： C07D487/06
- IPC分类号： C07D487/06 ; C07D209/14 ; C07D403/08 ; C07D209/32 ; C07C243/22 ; C07D487/04 ; C07D209/48 ; C07D403/06
摘要：
The present invention relates to a process for the preparation of rucaparib; the invention also refers to novel intermediates of synthesis as well as their use in the preparation of i.a. rucaparib.