Various embodiments to enable Spectrum Access System (SAS) interference mitigation options are disclosed herein. In one embodiment, an apparatus is provided. The apparatus includes a memory to store a data sequence, and one or more processing devices coupled to the memory. The processing devices to generate an interference metric associated with a first group and a second group of infrastructure nodes of a Long-Term Evolution (LTE) network infrastructure based on measurement information. The measurement information comprises measurements related to the transmission of data sequences associated with the first group and the second group. Thereupon, configuration settings are determined for infrastructure nodes of the first group and second group based on the generated interference metric. Each configuration setting represents a frequency band and transmission power level for a corresponding infrastructure node to access data in the LTE network infrastructure.