A heavy-duty pneumatic tire includes a section width being equal to or less than 335 mm, an aspect ratio being equal to or less than 55%, and a toroidal carcass extending between axially spaced bead portions through a tread portion and sidewall portions. The carcass includes a carcass ply which includes a main portion and a turn-up portion turned up around a bead core of each bead portion. A belt layer is disposed radially outward of the carcass in the tread portion, wherein a radially outer end of the turn-up portion is located between the main portion and the belt layer in the tread portion. A sheeted rubber layer is disposed between the main portion and the turn-up portions in each sidewall portion.