Invention Grant
- Patent Title: Near-infrared chemiluminescent probes for in-vivo imaging
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Application No.: US16616336Application Date: 2018-05-23
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Publication No.: US11241507B2Publication Date: 2022-02-08
- Inventor: Doron Shabat , Ori Green
- Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
- Applicant Address: IL Tel-Aviv
- Assignee: RAMOT AT TEL-AVIV UNIVERSITY LTD.
- Current Assignee: RAMOT AT TEL-AVIV UNIVERSITY LTD.
- Current Assignee Address: IL Tel-Aviv
- Agency: Knobbe, Martens, Olson & Bear, LLP
- International Application: PCT/IL2018/050558 WO 20180523
- International Announcement: WO2018/216013 WO 20181129
- Main IPC: A61B5/00
- IPC: A61B5/00 ; A61B8/00 ; A61B10/00 ; A61K49/00 ; C07D407/10
Abstract:
The present invention provides turn-ON dioxetane-based chemiluminescence probes based on the Schapp's adamantylidene-dioxetane probe, which emit light in the near-infrared (NIR) region and are therefore useful for in vivo imaging, as well as compositions and uses thereof.
Public/Granted literature
- US20200093942A1 NEAR-INFRARED CHEMILUMINESCENT PROBES FOR IN-VIVO IMAGING Public/Granted day:2020-03-26
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