A wireless communication device and a dynamic anti-interference method for the same are provided. The device includes at least two wireless communication circuits. When the method operates in the wireless communication device, the device monitors activities of every wireless communication circuit through a clear channel assessment method for acquiring signal strength of every wireless communication circuit. The assessment allows the device to perform a corresponding anti-interference measure for each of the wireless communication circuits. For example, when the device acknowledges that a second wireless communication circuit of the device starts to work as a first wireless communication circuit transmits or receives signals, the device controls a receiver or a transmitter of the second wireless communication circuit to perform an anti-interference measure such as a gain control for a receiver or power adjustment for a transmitter.