A virtual assistance system for a vehicle is provided. The virtual assistance system includes one or more processors, one or more memory modules communicatively coupled to the one or more processors, an input device communicatively coupled to the one or more processors, an output device communicatively coupled to the one or more processors, and machine readable instructions stored in the one or more memory modules. The virtual assistance system receives, through the input device, a request for an item from a user, retrieves a location of an entity associated the item, calculates an estimated arrival time when the vehicle will arrive at the location, compares the estimated arrival time with a predetermined time associated with the entity, and instructs the output device to generate a delivery prompt related to the item in response to comparing the estimated arrival time with the predetermined time.