Invention Grant
- Patent Title: Immuno-based botulinum toxin serotype A activity assays
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Application No.: US17124747Application Date: 2020-12-17
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Publication No.: US11261240B2Publication Date: 2022-03-01
- Inventor: Ester Fernandez-Salas , Joanne Wang , Patton E. Garay , Lina Wong , D. Diane Hodges , Kei Roger Aoki
- Applicant: Allergan, Inc.
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agency: Foley Hoag LLP
- Main IPC: C07K16/12
- IPC: C07K16/12 ; G01N33/569 ; C12Q1/37
Abstract:
The present specification discloses SNAP-25 compositions, methods of making α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing α-BoNT/A antibodies.
Public/Granted literature
- US20210171614A1 IMMUNO-BASED BOTULINUM TOXIN SEROTYPE A ACTIVITY ASSAYS Public/Granted day:2021-06-10
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