A method includes receiving a first transition probability matrix (TPM) of a subsurface region, wherein the TPM defines, for a given lithology at a current depth sample (or micro-layer), a probability of particular lithologies at a next depth sample (or micro-layer), receiving seismic data for the subsurface region, utilizing the first TPM and the seismic data to generate first pseudo wells, calculating a second TPM from the first pseudo wells, determining whether the second TPM is consistent with the first TPM, and utilizing the first pseudo wells to characterize a reservoir in the subsurface region when the second TPM is determined to be consistent with the first TPM.