A sensor system includes a sensing panel, at least one multiplexer and a controller. The sensing panel includes one or more sensing areas. The multiplexer is coupled to the one or more sensing areas through one or more connecting wire groups on the sensing panel, wherein each of the connecting wire groups includes one or more connecting wires. The controller is coupled to the at least one multiplexer via one or more control wires and one or more sensing wires. Each of the at least one multiplexer includes one or more switch groups each coupled between one of the one or more sensing wires and one of the connecting wire groups, and each of the switch groups includes one or more switches respectively controlled by one or more control signals transmitted through the one or more control wires.