- Patent Title: Antibodies that specifically bind to human IL-15 and uses thereof
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Application No.: US16471616Application Date: 2017-12-21
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Publication No.: US11267883B2Publication Date: 2022-03-08
- Inventor: David Jose Simon Laine , Matthew Pollard , Anthony Gerard Doyle , Lynn Dorothy Poulton , Adam William Clarke
- Applicant: Cephalon, Inc.
- Applicant Address: US PA Frazer
- Assignee: Cephalon, Inc.
- Current Assignee: Cephalon, Inc.
- Current Assignee Address: US PA Frazer
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- International Application: PCT/US2017/067917 WO 20171221
- International Announcement: WO2018/119246 WO 20180628
- Main IPC: C07K16/24
- IPC: C07K16/24 ; A61P37/00 ; A61P3/00 ; A61P29/02 ; A61P1/00 ; A61K39/00
Abstract:
Recombinant antibodies that specifically bind to IL-15 as well as a complex of IL-15 and the IL-15 Receptor-alpha are provided. The antibodies inhibit immune cell proliferation, and are capable of use in the treatment of any autoimmune or inflammatory disease or condition where IL-15 is dysregulated, including Celiac disease.
Public/Granted literature
- US20200270339A1 ANTIBODIES THAT SPECIFICALLY BIND TO HUMAN IL-15 AND USES THEREOF Public/Granted day:2020-08-27
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