A voltage regulation system, a driving circuit, a display device and a voltage regulation method are disclosed. The voltage regulation system, applicable to an electronic device, including a power supply circuit, a determination circuit and a regulation circuit. The power supply circuit is connected with the regulation circuit, and the power supply circuit is configured to provide a reference voltage and provide a first voltage inputted into the electronic device; the determination circuit is connected with the power supply circuit, and the determination circuit is configured to, according to the reference voltage and the first voltage, output a compensation voltage; and the regulation circuit is connected with the determination circuit so as to receive the compensation voltage, and the regulation circuit is configured to output a third voltage, according to the compensation voltage and a second voltage, in a case where the compensation voltage is not within a preset range.