Disclosed are a respirator and a handling method, a control system, a program and a readable medium thereof. The respirator comprises blowers and an airflow output channel which communicates with the corresponding one of the blowers. The blowers include a first blower and a second blower; an air inlet of the second blower communicates with an air outlet of the first blower, and an air outlet of the second blower communicates with the airflow output channel. The respirator of the disclosure adopts a power structure which includes the first blower and the second blower, wherein the first blower as an air supply source supplies air to the second blower to obtain a two-level pressure boosting effect.