A pressure sensing device, a display panel and a method of manufacturing the same, and a display device are provided. The pressure sensing device includes a columnar electrode assembly having at least one columnar electrode and at least one columnar insulating layer that are alternately stacked in an axial direction of a columnar electrode, and an annular electrode assembly that is disposed around the columnar electrode assembly. The annular electrode assembly includes at least one annular electrode and at least one annular insulating layer that are alternately stacked in the axial direction of the columnar electrode. The annular electrode assembly and the columnar electrode assembly are insulated from each other, and are configured to form a capacitor. At least one of the at least one annular insulating layer and the at least one columnar insulating layer is an elastic insulating layer.