A seat assembly may include a seat having a seat base and a seat back, a temperature control unit disposed at least partially in the seat back, and/or an ECU connected with the temperature control unit. The ECU may be configured to receive an input related to (i) a first state corresponding to symptoms and/or discomfort associated with dysmenorrhea and/or (ii) a second state corresponding to symptoms and/or discomfort associated with sciatica. The ECU may be configured to operate the seat assembly according, at least in part, to the input.