Methods, systems, and apparatus, including computer-readable media, are described for interleaving memory requests to accelerate memory accesses at a hardware circuit configured to implement a neural network model. A system generates multiple requests that are processed against a memory of the system. Each request is used to retrieve data from the memory. For each request, the system generates multiple sub-requests based on a respective size of the data to be retrieved using the request. The system generates a sequence of interleaved sub-requests that includes respective sub-requests of a first request interleaved among respective sub-requests of a second request. Based on the sequence of interleaved sub-requests, a module of the system receives respective portions of data accessed from different address locations of the memory. The system processes each of the respective portions of data to generate a neural network inference using the neural network model implemented at the hardware circuit.