- 专利标题： Methods for determining a patient's susceptibility of contracting a nosocomial infection and for establishing a prognosis of the progression of septic syndrome
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申请号： US13140678申请日： 2010-01-18
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公开(公告)号： US11299768B2公开(公告)日： 2022-04-12
- 发明人: Marie-Angelique Cazalis , Alain Lepape , Guillaume Monneret , Bruno Mougin , Alexandre Pachot
- 申请人： Marie-Angelique Cazalis , Alain Lepape , Guillaume Monneret , Bruno Mougin , Alexandre Pachot
- 申请人地址： FR Vaulx en Velin; FR Saint-Genis Laval; FR Lyons; FR Lyons; FR Sulignat
- 专利权人： Marie-Angelique Cazalis,Alain Lepape,Guillaume Monneret,Bruno Mougin,Alexandre Pachot
- 当前专利权人： Marie-Angelique Cazalis,Alain Lepape,Guillaume Monneret,Bruno Mougin,Alexandre Pachot
- 当前专利权人地址： FR Vaulx en Velin; FR Saint-Genis Laval; FR Lyons; FR Lyons; FR Sulignat
- 代理机构： Oliff PLC
- 优先权： FR0950305 20090119,FR0950306 20090119
- 国际申请： PCT/FR2010/050070 WO 20100118
- 国际公布： WO2010/082004 WO 20100722
- 主分类号： C12Q1/6809
- IPC分类号： C12Q1/6809 ; C12Q1/686 ; C12Q1/6886 ; C12Q1/6876 ; C12Q1/6865 ; C12Q1/6813 ; C12Q1/6883
摘要：
A method for determining a patient's susceptibility of contracting a nosocomial infection that includes obtaining a biological sample from the patient and extracting biological material from the biological sample; preparing a specific reagent of an expression product of at least one target gene selected from S100A9 and S100A8 target genes; and determining the expression of at least one of the target genes S100A9 and S100A8, where overexpression relative to a specified threshold value indicates susceptibility of contracting a nosocomial infection.
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