A refrigerator includes a storage space, a freezing chamber defining an insulating space configured to maintain a chamber temperature independent from the storage space, an evaporator in the storage space, a grille panel assembly that defines an evaporator space configured to accommodate the evaporator and at least a portion of the storage space, a thermoelectric element assembly including a thermoelectric element, a heat sink, and a cold sink to cool the freezing chamber to a temperature less than the temperature of the storage space, a module accommodation portion located at a side of the grille panel assembly, a defrost water guide that communicates with the module accommodation portion and the evaporator space and that is configured to discharge defrost water generated during a defrost operation of the freezing chamber, and a defrost heater located in the module accommodation portion and configured to melt ice during the defrost operation.