Disclosed are apparatuses and methodologies for achieving current inventory data management with an electronic access control system. An access control system provides access control data while a sealed enclosure incorporates an RFID reading system for determining the identity of respective tagged contents therein. Particularly in conjunction with the storage of controlled substances, such as some drugs utilized on an EMS vehicle, a tamper evident RFID tag is fully or partially destroyed or damaged, or otherwise impacted or affected so as to generate a changed ID, whenever the contained medicinal dosage is acquired for administration. Specific container/cap combinations accommodate various drug dosages, and are combinable with tamper evident RFID tags. Usage of tagged drugs may be tracked by reading narcotics box contents before and after a work shift. Intra-shift access and usage reports at each point of consumption maintains a complete record of custody of control.