A semiconductor device includes an active region extending from a substrate in a vertical direction, source/drain regions spaced apart from each other on the active region, a fin structure between the source/drain regions on the active region, the fin structure including a lower semiconductor region on the active region, a stack structure having alternating first and second semiconductor layers on the lower semiconductor region, a side surface of at least one of the first semiconductor layers being recessed, and a semiconductor capping layer on the stack structure, an isolation layer covering a side surface of the active region, a gate structure overlapping the fin structure and covering upper and side surfaces of the fin structure, the semiconductor capping layer being between the gate structure and each of the lower semiconductor region and stack structure, and contact plugs electrically connected to the source/drain regions.