A wireless communication system includes: a first sub-system including a first radio and a second radio, each including a transceiver or a receiver; and a second sub-system coupled to the first sub-system and including: a first antenna configured to convey signals; a first tuner coupled to the first antenna; and a controller coupled to the first tuner, the controller being configured to cause the first tuner to adjust a characteristic of the first tuner; where the controller and/or the first tuner is configured to provide, to the first sub-system, an indication of an effect on operational performance of a portion of the second sub-system coupled to the second radio based on operation of the first tuner or the first antenna, or a combination thereof; where the first sub-system is configured to modify operation of the second radio based on the indication of the effect on operational performance.