The present disclosure relates to systems and methods for mixing and injecting fluid treatment, such as cement to treat bone or hard tissue. In some embodiments, a mixing apparatus may facilitate mixing within a syringe. Additionally, the syringe may be configured to extract bone cement from a cement mixer. A syringe for mixing and injecting cement may include a detachable handle that may be detached after extracting bone cement from a mixer to facilitate coupling to a high-pressure syringe for injection.