A resettable inertia lock assembly may include a chassis configured to be mounted within an access closure of a motor vehicle, a cassette, a reset structure defined on one of the chassis and the cassette, a resettable locking apparatus carried by the cassette and including an inertia-activated member and an engagement coupler, the engagement coupler movable between a first position securing the inertia-activated member in an inertia-activated position and a second position in which the engagement coupler does not secure the inertia-activated member in the inertia-activated position, and a movement device for producing a relative movement between the chassis and the cassette to cause the reset structure to engage and move the engagement coupler from the first position to the second position thereof to allow the inertia-activated member to move from the inertia-activated position to a home position.