![Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors](/docs/US/2022-05-17/US11331320B2/abs.jpg.600x600.jpg)
- 专利标题： Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
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申请号： US16821624申请日： 2020-03-17
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公开(公告)号： US11331320B2公开(公告)日： 2022-05-17
- 发明人: James D. Rodgers , Stacey Shepard
- 申请人： Incyte Corporation , Incyte Holdings Corporation
- 申请人地址： US DE Wilmington; US DE Wilmington
- 专利权人： Incyte Corporation,Incyte Holdings Corporation
- 当前专利权人： Incyte Corporation,Incyte Holdings Corporation
- 当前专利权人地址： US DE Wilmington; US DE Wilmington
- 代理机构： Fish & Richardson P.C.
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61P29/00 ; A61P35/04 ; C07D471/04 ; C07D487/04 ; C07D417/04 ; A61K31/573 ; A61K45/06 ; A61P17/04 ; A61K9/00 ; A61K9/20 ; C07B59/00
![Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors](/abs-image/US/2022/05/17/US11331320B2/abs.jpg.150x150.jpg)
摘要：
The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.
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