An engine valve actuation system includes a hydro-mechanical valve actuation module having a first hydro-mechanical linkage and a second hydro-mechanical linkage, each within a different housing block of a housing. Each of the first hydro-mechanical linkage and the second hydro-mechanical linkage includes a cam-follower piston in contact with a cam of a camshaft, and a valve-actuation piston hydraulically co-acting with the respective cam-follower piston. The hydro-mechanical valve actuation module may include hydro-mechanical linkages for an intake valve, for an exhaust valve, and for engine braking.