A pixel driving method is provided. Based on current brightness values of the sub-pixel in row j and column i, current brightness values of the sub-pixels that have the same color and are adjacent to the sub-pixel in row j and column i to obtain the target brightness value of the sub-pixel in row j and column i by the target brightness value calculation formula, and then to obtain a brightness compensation value of the sub-pixel in row j and column i by a brightness compensation value calculation formula, and based on the target brightness value of the sub-pixel in row j and column i, the brightness compensation value of the sub-pixel in row j and column i to output a compensated brightness value of the sub-pixel in row j and column i by a compensated brightness value calculation formula.