A vape cleaning device for easily and thoroughly cleaning vape coils for reuse and avoiding the need for frequent replacement. The device has a base enclosing a fan oriented to direct air upwardly, a heat block suspended above the fan, a heating element coupled to the heat block, and a shield coupled to the base and having a central opening. A cup is removably positioned in the central opening of the shield and in contact with the heat block to be heated thereby. A vape coil holder may removably suspended in the cup that the vape coil is submerged in a cleaning fluid in the cup. After the cup has been warmed to a predetermined temperature for a cleaning cycle, the cup may be removed and the vape coil holder suspended from the shield. The fan may then be operated for a predetermined time period for a drying cycle.