- 专利标题： Method for delivering RNA to neurons to treat herpes infections
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申请号： US16312277申请日： 2017-06-21
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公开(公告)号： US11351273B2公开(公告)日： 2022-06-07
- 发明人: David C. Bloom , Alfred S. Lewin , Donna M. Neumann , Zachary L. Watson , Sonal Sanjeev Tuli , Gregory Scott Schultz
- 申请人： University of Florida Research Foundation, Incorporated , Board of Supervisors Of Louisiana State University & Agricultural & Mechanical College
- 申请人地址： US FL Gainesville; US LA Baton Rouge
- 专利权人： University of Florida Research Foundation, Incorporated,Board of Supervisors Of Louisiana State University & Agricultural & Mechanical College
- 当前专利权人： University of Florida Research Foundation, Incorporated,Board of Supervisors Of Louisiana State University & Agricultural & Mechanical College
- 当前专利权人地址： US FL Gainesville; US LA Baton Rouge
- 代理机构： Wolf, Greenfield & Sacks, P.C.
- 国际申请： PCT/US2017/038618 WO 20170621
- 国际公布： WO2017/223248 WO 20171228
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; A61K48/00 ; C12N15/113 ; C12N15/86 ; A61P31/22 ; C12N5/0793
摘要：
Aspects of the application relate to methods and compositions for delivering therapeutic nucleic acids to neural cells or tissue in a subject. Additional aspects of the application relate to therapeutic nucleic acids, for example therapeutic ribozymes, that are useful for inhibiting viral reactivation in a subject.
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