A method for managing several queues of a network interface card (NIC) of a computer. The method initially configures the NIC to direct data messages received for a data compute node (DCN) executing on the computer to a default first NIC queue. When the DCN requests data messages addressed to the particular DCN to be processed with a first feature for load balancing data messages across multiple queues and a second feature for aggregating multiple related data messages into a single data message, the method configures the NIC to direct subsequent data messages received for the DCN to a second queue in a first subset of queues associated with the first feature if a load on the default first queue exceeds a first threshold. Otherwise, if a load on the first subset of queues exceeds a second threshold, the method configures the NIC to direct subsequent data messages received for the particular DCN to a third queue in a second subset of queues associated with both the first and second features.