- Patent Title: C40-, C28-, and C-32-linked rapamycin analogs as mTOR inhibitors
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Application No.: US17083172Application Date: 2020-10-28
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Publication No.: US11364300B2Publication Date: 2022-06-21
- Inventor: Jennifer Pitzen , G. Leslie Burnett , James Bradley Aggen
- Applicant: Revolution Medicines, Inc.
- Applicant Address: US CA Redwood City
- Assignee: Revolution Medicines, Inc.
- Current Assignee: Revolution Medicines, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Cooley LLP
- Main IPC: C07D498/18
- IPC: C07D498/18 ; C07D519/00 ; A61K31/436 ; A61K31/519 ; A61K31/553 ; A61K47/54

Abstract:
The present disclosure relates to mTOR inhibitors. Specifically, the embodiments are directed to compounds and compositions inhibiting mTOR, methods of treating diseases mediated by mTOR, and methods of synthesizing these compounds.
Public/Granted literature
- US20210338824A1 C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors Public/Granted day:2021-11-04
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