A system, method and a network architecture for facilitating remote care therapy via secure communication channels between clinicians and patients having one or more IMDs, wherein certain unique information retrieved from an IMD is used in association with an encryption key infrastructure system for establishing trusted relationships between a clinician device, a patient's device and the patient's IMD. A cloud-based remote care session manager is provided for registering and validating the clinician and patent devices based on the IMD data used as trust indicia. In one embodiment, trusted associations between the devices are only established when the devices in close proximity of each other, e.g., in an in-person setting.