Disclosed are systems and methods of accessing content items stored at a content management system by a mobile device, when the mobile device is not communicatively coupled to the content management system. The content management system can receive an indication to mark a content item (e.g., folder and the content items associated with the folder) as available to a mobile device when the mobile device is offline. The content management system can mark the content item, and any content items associated with the content item, for offline access by the mobile device and determine a synchronization schedule for the content item(s). The content management system can then initially send to the mobile device, the marked content item(s) in accordance with the synchronization schedule. While offline, the mobile device can make changes to the marked content items. The changes can be synchronized between the mobile device and content management system when the mobile device is online.